Ketosis: Ketone production and metabolism.

Ketosis:  Ketone production and metabolism.

This is a short video  lecture covering the basics of ketone production and metabolism.  It is a “big picture” overview only.  It will give you a firm understanding of why ketones are produced and how they are metabolized for energy.

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Type 2 diabetes part II – What you can do about it.

Type 2 diabetes part II – What you can do about it.

In part II I present research and discuss some simple actions you can take to help to manage and even reverse your diabetes.  

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How to design run training programs – video lecture

How to design run training programs – video lecture

This is a video lecture describing how to write run training programs for every race distance from 1 mile to ultra marathons.  It includes basic information on how to monitor intensity and what physiologic adaptations occur in each training zone.  The basic periodized template includes 3 tools and 3 phases.   I hope you find it to be useful.

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Type II Diabetes – Etiology and Development

Type II Diabetes – Etiology and Development

In this lecture I discuss the leading theory of how type II diabetes develops.  I also discuss how insulin resistance can be detected early and some of the pathology associated with elevated insulin and glucose.

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The Science of Muscle Hypertrophy

The Science of Muscle Hypertrophy

In this short lecture I will discuss some of the physiology of muscle hypertrophy and some findings from a recent review of the research literature.

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Why HIIT does not burn much fat, and why it doesn’t matter

Why HIIT does not burn much fat, and why it doesn’t matter

 

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My Experience With the Ketogenic Diet – With Advanced Lipid Testing

My Experience With the Ketogenic Diet – With Advanced Lipid Testing

This short video shows some advanced lipid testing during my trial run of the ketogenic diet.  I was on the keto diet for 4 1/2 months and did some advanced lipid testing to track my blood lipids.  My blood lipid response was a bit unusual and in fact, had me a bit concerned.  In this video I explain the basics of advanced lipid testing and […]

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Rich or Poor?

Rich or Poor?

  My wife and I have a little inside joke, “Are we rich or are we poor?”  I retired at 48 and never have to work again, so we must be rich, right?   But we have only 1 car, live in a studio apartment, and have a grand total of $100 worth of furniture, so we must be poor, right?  We live in a very […]

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Why you don’t burn much fat during HIT and why it does not matter.

Why you don’t burn much fat during HIT and why it does not matter.

As exercise intensity increases, you release more “fight or flight”  and catabolic hormones. Insulin production decreases but many other hormones increase.  Note that HIT is performed at or near 100% VO2 max typically. Epinehprine is a strong activator of hormone sensitive lipase, which is the enzyme in the adipocyte (fat cell) that breaks down triglycerides into fatty acids and glycerol.  So….you would think that at […]

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Why does endurance exercise interfere with muscle growth?

Why does endurance exercise interfere with muscle growth?

Image from Exercise Physiology, Theory and Application to Fitness and Performance by Powers and Howley. In the figure above, endurance exercise results in a signaling cascade in the muscle driven by the depletion of ATP among other things. ADP and AMP accumulation cause the increase in AMP Kinase, and then TSC1/2 downstream. TSC1/2 inhibits mTOR. mTOR is part of the anabolic signaling cascade in muscle […]

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